Methodology

No more gatekeepers.
Here's how.

Every OPTIMIZE protocol is evidence-cited and reproducible. Two people with the same inputs get the same protocol — every time. The specifics of your protocol trace to published research, not to someone's opinion. This replaces the need for gatekeepers.

Intake
clinical questions
Match
to the evidence
Protocol
three zones
Track
90-day cycle
Step 1 of 4

Clinical intake

You answer a structured clinical intake per domain — baselines, symptoms, goals, history, lifestyle. No free text, no opinion capture. Answers that raise a safety flag halt the self-directed output and route you directly to clinician territory.

Step 2 of 4

Evidence-matched protocol

Your answers are matched to a library of interventions that are each tied to peer-reviewed evidence. The matching is reproducible — the same answers always produce the same protocol. No model at runtime, no generated recommendations.

Every entry in your protocol carries the evidence it stands on.

Step 3 of 4

Three-zone output

Your protocol is split into three zones so you always know what you can do yourself and what needs a clinician:

Zone 1 — Measurement
Labs to order. Biomarkers with optimal ranges. The things you need to know your own numbers.
Zone 2 — Self-directed
OTC compounds, dietary levers, training, sleep, light. Legal to act on yourself. Every entry carries a dose range and effect size cited to published evidence.
Zone 3 — Clinician
Prescription options and clinical evaluations. OPTIMIZE does not prescribe. Each card names the option and includes the exact question to ask your doctor.
Step 4 of 4

Track, re-intake, evolve

Interventions and biomarker readings are logged over time. The tracking page renders a chart per biomarker with your personalized reference band, any goal line you set, and vertical pins at every date you started an intervention — so you can see which changes correlate with which readings.

At day 90 you're prompted to re-intake. Your earlier answers are the default; you edit what changed. The protocol evolves with your data, not with a marketing calendar.

Why it matters

Reproducibility is the feature.

If you're going to follow a protocol for twelve weeks, you deserve to know that a friend with the same answers would get the same protocol — and that six months from now, your answers would still route to the same recommendations unless the published evidence itself has changed.

Every recommendation you see is backed by peer-reviewed studies you can read. You don't have to trust us. You don't have to trust a gatekeeper. You have to trust the evidence.

Testimonials

Honest about where we are.

No testimonials yet

Testimonials go here once the first beta users finish their 12-week cycles and can speak to what actually moved. We will not fabricate them, stage them, or pay for them. When a real user writes in and gives permission, their words land in this slot — name, role, verbatim, and when they sent it.

Finished a cycle and want to share what changed? Reply to any OPTIMIZE email →

7-day refund · 30-day unused-session refundwhen pricing lands

OPTIMIZE · a protocols.is product