Side-by-side · Longevity supplement stack + content

OPTIMIZE vs Blueprint

Blueprint is Bryan Johnson's personal supplement + lifestyle stack, sold as a kit. Radically transparent about protocol, but it's one stack for one person — yours looks identical regardless of your baseline, biomarkers, or goals.

OPTIMIZE
$147 / year

1 year of product + lifetime community. All 6 domains included.

Blueprint
$3996 / year

$333/month for the full stack kit (Longevity Protocol)

MathOPTIMIZE is 27.2× cheaper — you save $3,849/year.

Feature-by-feature

Feature
OPTIMIZE
Blueprint
Personalized to your biomarkers
OPTIMIZE: Routed from your intake + lab imports.
Blueprint: Same stack for every customer.
Evidence-tier knob (Conservative / Standard / Aggressive)
Citations on every recommendation
Blueprint: Selected citations; full protocol rationale not always linked to PMIDs.
Cycle + PCT planning for Z3 compounds
Re-intake every 90 days
PDF protocol for your clinician
Supplement kit shipped to your door
OPTIMIZE: Future founder-led product line planned; for now you self-source with our compound library as reference.
Community / forum
OPTIMIZE: Lifetime community with your $147.
Founder session
OPTIMIZE: Evolutionary Analysis with the founder — $297 / 1 hr or $1,200 / 6-pack, capped at 8 bookings/month.

Ready to run a protocol?

OPTIMIZE builds a personalized protocol across six domains in 60 seconds. No signup gate — see your first insight before creating an account.

OPTIMIZE · a protocols.is product

Comparison current as of 2026-04-22. Competitor pricing and feature lists drift; we update this page periodically. Trademarks belong to their respective owners; this comparison is editorial content, not endorsement or affiliation.